GAO Ling

Personal Information

Name GAO Ling
School or College School of Medicine
Position TitleAssociate Prof. Associate Chief Physician
Office Address

Research Interest

Diabetes and its complications

Obesity and its mechanism

Hepatic steatosis and insulin resistance


2002-2006·  K C Wong Ph.D. Scholar, Cardiovascular Division

             School of Biomedical &Health Sciences

             King’s College London, London SE1 9UL, UK

2001-2002    Ph.D Candidate, Endocrinology Division,

             RuiJin Hospital, Second Shanghai Medical University, Shanghai, China

             Left due to the award of K C Wong Scholarship for King’s College London

1996-1999    Postgraduate Degree: Endocrinology & Metabolism, 

             Hubei Medical University, Wuhan, China

1991-1996    M.B.:  Hubei Medical University, Wuhan, China

Oversea Study and Visit

2006-2010     Postdoctoral Researcher, Division of Molecular Medicine

              Department of Anesthesiology, University of California at Los Angeles

              Los Angeles CA 90095, USA

2006-2006        Postdoctoral Researcher, Cardiovascular Section,

              Department of Medicine, University of Chicago, Chicago, IL, USA

2002-2006·   K C Wong Ph.D. Scholar, Cardiovascular Division

             School of Biomedical &Health Sciences

             King’s College London, London SE1 9UL, UK

Honours and Awards

National and International Awards, grants, memberships and associations


2002‐2005  K C Wong Ph.D. Scholarship (£24,000 per annual for 3 years)

           Awarded by King’s College London and China Scholarship Council



2012‐2015      NSFC: 81170767   

2012-2014      China Young Scientist fund   

2014-2016      China Medical Society Diabetes Studying fund


Memberships of Learned Societies

2002-         The Physiological Society, U.K. (Affiliate Member and Full Member in 2009)

2008-         Reviewer for Free Radical Biology & Medicine

2009-         Reviewer for International Journal of Cardiology

2009-         Reviewer for British Journal of Pharmacology

2014-         Member of Chinese Medical Society, Obesity Group

2014-         Editorial Board of World Chinese Journal of Gastroenterology 


Gao L, Huang W, Li J. NOX1 abet mesangial fibrogenesis via iNOS induction in diabetes. Mol Cell Biochem. 2013 Oct;382(1-2):185-91. doi: 10.1007/s11010-013-1733-4. Epub 2013 Jun 26.


Youn JY, Gao L, Cai H. The p47phox and NOXO1-dependent Activation of NOX1 Mediates eNOS Uncoupling and Endothelial Dysfunction in Streptozotocin Induced Diabetic Mice. Diabetologia. 2012 Jul;55(7):2069-79.


Gao L, Siu KL, Chalupsky K, Nguyen A, Chen P, Weintraub NL, Galis Z, Cai H. Role of uncoupled endothelial nitric oxide synthase in abdominal aortic aneurysm formation: treatment with folic Acid.  Hypertension. 2012 Jan; 59(1):158-66.


Mao T, Gao L, Li H, Li J. Pigment epithelium‐derived factor inhibits high glucose induced oxidative stress and fibrosis of cultured human glomerular mesangial cells. Saudi Med J. 2011 Aug;32(8):769‐77.


He M, Siow RCM, Sugden D, Gao L, Cheng X, Mann GE. Induction of HO‐1 and redox signaling in endothelial cells by advanced glycation end products: A role for Nrf2 in vascular protection in diabetes. Nutr Metabol Cardiovasc Dis. 2011 Apr;21(4):277-85.


Gao L, Mann GE. Vascular NAD(P)H oxidase activation in diabetes: a double-edged sword in redox signaling. Cardiovasc Res. 2009; 82(1): 9-20.


Gao L, Chalupsky K, Stefani E, Cai H. Mechanistic insights into folic acid-dependent vascular protection: Dihydrofolate reductase (DHFR)-mediated reduction in oxidant stress in endothelial cells and angiotensin II-infused mice: A novel HPLC-based fluorescent assay for DHFR activity. J Mol Cell Cardiol. 2009; Dec; 47(6):752-60.


Gao L, Pung YF, Zhang J, Chen P, Wang T, Li M, Meza M, Toro L, Cai H. Sepiapterin Reductase Regulation of Endothelial Tetrahydrobiopterinand Nitric Oxide Bioavailability. Am J Physiol Heart Circ Physiol.  2009; 297 (1): H331-9.


Gao L, Laude K, Linda (Hua) Cai. Mitochondrial pathophysiology, reactive oxygen species and cardiovascular diseases.  Vet Clin N Am-Small. 2008; 38 (1): 137-155.


Mann GE, Niehueser-Saran J, Watson A, Gao L, Ishii T, de Winter P, Siow RC. Nrf2/ARE regulated antioxidant gene expression in endothelial and smooth muscle cells in oxidative stress: implications for atherosclerosis and preeclampsia. Acta Physiologica Sinica. 2007; 59(2):117-127.