GAO Ling

Personal Information

Name GAO Ling
School or College School of Medicine
GenderMale
Position TitleAssociate Prof. Associate Chief Physician
Phone15927469449
Website
Emailling.gao@medmail.com.cn
Office Address

Research Interest

Diabetes and its complications

Obesity and its mechanism

Hepatic steatosis and insulin resistance


Education

2002-2006·  K C Wong Ph.D. Scholar, Cardiovascular Division

             School of Biomedical &Health Sciences

             King’s College London, London SE1 9UL, UK

2001-2002    Ph.D Candidate, Endocrinology Division,

             RuiJin Hospital, Second Shanghai Medical University, Shanghai, China

             Left due to the award of K C Wong Scholarship for King’s College London

1996-1999    Postgraduate Degree: Endocrinology & Metabolism, 

             Hubei Medical University, Wuhan, China

1991-1996    M.B.:  Hubei Medical University, Wuhan, China


Oversea Study and Visit

2006-2010     Postdoctoral Researcher, Division of Molecular Medicine

              Department of Anesthesiology, University of California at Los Angeles

              Los Angeles CA 90095, USA

2006-2006        Postdoctoral Researcher, Cardiovascular Section,

              Department of Medicine, University of Chicago, Chicago, IL, USA

2002-2006·   K C Wong Ph.D. Scholar, Cardiovascular Division

             School of Biomedical &Health Sciences

             King’s College London, London SE1 9UL, UK


Honours and Awards

National and International Awards, grants, memberships and associations

Awards:

2002‐2005  K C Wong Ph.D. Scholarship (£24,000 per annual for 3 years)

           Awarded by King’s College London and China Scholarship Council

 

Grants

2012‐2015      NSFC: 81170767   

2012-2014      China Young Scientist fund   

2014-2016      China Medical Society Diabetes Studying fund

 

Memberships of Learned Societies

2002-         The Physiological Society, U.K. (Affiliate Member and Full Member in 2009)

2008-         Reviewer for Free Radical Biology & Medicine

2009-         Reviewer for International Journal of Cardiology

2009-         Reviewer for British Journal of Pharmacology

2014-         Member of Chinese Medical Society, Obesity Group

2014-         Editorial Board of World Chinese Journal of Gastroenterology 


Publications

Gao L, Huang W, Li J. NOX1 abet mesangial fibrogenesis via iNOS induction in diabetes. Mol Cell Biochem. 2013 Oct;382(1-2):185-91. doi: 10.1007/s11010-013-1733-4. Epub 2013 Jun 26.

 

Youn JY, Gao L, Cai H. The p47phox and NOXO1-dependent Activation of NOX1 Mediates eNOS Uncoupling and Endothelial Dysfunction in Streptozotocin Induced Diabetic Mice. Diabetologia. 2012 Jul;55(7):2069-79.

 

Gao L, Siu KL, Chalupsky K, Nguyen A, Chen P, Weintraub NL, Galis Z, Cai H. Role of uncoupled endothelial nitric oxide synthase in abdominal aortic aneurysm formation: treatment with folic Acid.  Hypertension. 2012 Jan; 59(1):158-66.

 

Mao T, Gao L, Li H, Li J. Pigment epithelium‐derived factor inhibits high glucose induced oxidative stress and fibrosis of cultured human glomerular mesangial cells. Saudi Med J. 2011 Aug;32(8):769‐77.

 

He M, Siow RCM, Sugden D, Gao L, Cheng X, Mann GE. Induction of HO‐1 and redox signaling in endothelial cells by advanced glycation end products: A role for Nrf2 in vascular protection in diabetes. Nutr Metabol Cardiovasc Dis. 2011 Apr;21(4):277-85.

 

Gao L, Mann GE. Vascular NAD(P)H oxidase activation in diabetes: a double-edged sword in redox signaling. Cardiovasc Res. 2009; 82(1): 9-20.

 

Gao L, Chalupsky K, Stefani E, Cai H. Mechanistic insights into folic acid-dependent vascular protection: Dihydrofolate reductase (DHFR)-mediated reduction in oxidant stress in endothelial cells and angiotensin II-infused mice: A novel HPLC-based fluorescent assay for DHFR activity. J Mol Cell Cardiol. 2009; Dec; 47(6):752-60.

 

Gao L, Pung YF, Zhang J, Chen P, Wang T, Li M, Meza M, Toro L, Cai H. Sepiapterin Reductase Regulation of Endothelial Tetrahydrobiopterinand Nitric Oxide Bioavailability. Am J Physiol Heart Circ Physiol.  2009; 297 (1): H331-9.

 

Gao L, Laude K, Linda (Hua) Cai. Mitochondrial pathophysiology, reactive oxygen species and cardiovascular diseases.  Vet Clin N Am-Small. 2008; 38 (1): 137-155.

 

Mann GE, Niehueser-Saran J, Watson A, Gao L, Ishii T, de Winter P, Siow RC. Nrf2/ARE regulated antioxidant gene expression in endothelial and smooth muscle cells in oxidative stress: implications for atherosclerosis and preeclampsia. Acta Physiologica Sinica. 2007; 59(2):117-127.