Chengzhang Li

Personal Information

Name Chengzhang Li
School or College School of Stomatology
Position TitleProfessor
Office AddressNo.237 Luo Yu Road, Hongshan District, Wuhan

Research Interest

·Host factor of periodontitis

·Periodontal tissues Regeneration

·Occlusion and periodontitis


·1978-1983  Hubei Medical College     DDS

·1985-1988  Hubei Medical College     MS  

·1992-1995  Hubei Medical University   PhD

Oversea Study and Visit

·1998 Communicated and studied in Unilever Co., United Kingdom

Honours and Awards

· Inaugural medical innovation study of oral Award. CSA

· Science and Technology Award2.CSA

· Science and Technology Progress Award2. Hubei Provincia

· Teaching Achievement Award 1. Hubei Provincial


corresponding author

? Rose-bengal-conjugated gold nanorods for in vivo photodynamic and photothermal oral cancer therapies. Biomaterials. 2014:35:1954-1966. IF:8.312

? Bimodal optical diagnostics of oral cancer based on Rose Bengal conjugated gold nanorod platform. Biomaterials. 2013:34(17):4274-4283. IF:8.312

? Paper-based plasmonic platform for sensitive, noninvasive, and rapid cancer screening. Biosensors and Bioelectronics. 2013:54(15):128-134. IF:6.451

? Cyclic stretch stimulates recruitment of active Na+/K+-ATPase subunits to the plasma membrane of skeletal muscle cells. Mol Cell Biochem. 2012:366:299-308. IF:2.35

? Scaling and root planing with enhanced root planing on healthcare for type 2 diabetes mellitus: A randomized controlled clinical trial. Journal of Dental Sciences. 2013:8:272-280. IF:0.34

? Over-expression and potential role of cyclophilin A in human periodontitis. Journal of Periodontal Research. 2013:48(5):615-22. IF:1.99

? Temporal expression of metalloproteinase-8 and -13 and their relationships with extracellular matrix metalloproteinase inducer in the development of ligature-induced periodontitis in rats. Journal of Periodontal Research. 2013:48:411-419. IF:1. 99 

? Inhibitory effects of baicalin on IL-1 beta- induced MMP-1/TIMP-1 and its stimulated effect on Collagen-I production in human periodontal ligament cells. European Journal of Pharmacology. 2010:641(1): 1-6. IF:2.59

? The temporal expression and localization of extracellular matrix metalloproteinase inducer (EMMPRIN) during the development of perio-dontitis in an animal model. Journal of Periodontal Research. 2010:45(4): 541-549. IF:2.128

? Effect of matrix metalloproteinase-1 promoter genotype on interleukin-1beta-induced matrix metalloproteinase-1 production in human periodontal ligament cells. Journal of Periodontal Research. 2009:45(1):109-115. IF:2.128

? Cyclophilin A (CypA) is associated with the inflammatory infiltration and alveolar bone destruction in an experimental periodontitis. Biochemical and Biophysical Research Communications. 2010:391(1): 1000-1006. IF:2.4

? Expression of matrix metalloproteinase-1, matrix metalloproteinase-2 and extracellular metalloproteinase inducer in human periodontal ligament cells stimulated with interleukin-1beta. Journal of Periodontal Research. 2009:44(6): 784-793. IF:1.966

? Expression of extracellular matrix metalloproteinase inducer (EMMPRIN) in healthy and inflamed human gingiva. Quintessence International. 2009:40(8):683-690. IF:0.635

? Expression of extracellular matrix metalloproteinase inducer and enhancement of the production of matrix metalloproteinase-1 in tongue squamous cell carcinoma. International Journal of Oral and Maxillofacial Surgery.2009:38(8):880-885. IF:1.444

? Increased expression of extracellular matrix metalloproteinase inducer is associated with matrix metalloproteinase-1 and-2 in gingival tissues from patients with periodontitis. Journal of Periodontal Research. 2009:44(1):125-132. IF:1.966

? Intermittent PTH administration: A novel therapy method for periodontitis-associated alveolar bone lossMedical Hypotheses. 2009:72(3):294-296. IF:1.393

? Toll-like receptors 2 and 4 gene polymorphisms in a Chinese population with periodontitis. Quintessence International.2008:39(3):217-226. IF:0.71

? Protective effects of baicalin on ligature-induced periodontitis in rats. Journal of Periodontal Research. 2008:43(1):14-21. IF:2.038

? A potential role of EMMPRIN by regulating ECM degradation in periodontitis. Medical Hypotheses. 2007:69(5): 1102-1104. IF:1.054

? Inhibitory effect of flavonoid baicalin on degranulation of human polymorphonuclear leukocytes induced by interleukin-8: Potential role in periodontal diseases. Journal of Ethnopharmacology. 2007:109(2):325-330. IF:2.755

? Rose bengal staining in detection of oral precancerous and malignant lesions with colorimetric evaluation: A pilot study. International Journal of Cancer. 2007:120(9):1958-1963. IF:6.198

? MMP-1 promoter gene polymorphism and susceptibility to chronic periodontitis in a Chinese population. Tissue Antigens. 2006:68(1):38-43. IF:2.934

? A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter enhances oral squamous cell carcinoma susceptibility in a Chinese population. Oral Oncology. 2006:42(1):32-38. IF:2.695

? Association of matrix metalloproteinase-1 promoter polymorphism with generalized aggressive  periodontitis in a Chinese population. Journal of Periodontal Research. 2005:40(6):427-431. IF:1.947