Personal Information
Name | Yin Shen | ![]() |
School or College | School of Medicine | |
Gender | Female | |
Position Title | Associate Professor Associate Chief | |
Website | ||
yinshen@whu.edu.cn | ||
Office Address | Wuhan University Renmin Hospital |
Research Interest
Retinal Ocular fundus disease
Visual signal transmission mechanism
Education
1996 -2001 Wuhan University MD
2001-2006 Fudan University PhD
Oversea Study and Visit
2006 -2010 Einstein College of Medicine Research Associate
2013.10 Stanford University Visiting Professor
Honours and Awards
2010 Luojia Young Scholar of Wuhan University
2011 Youth Science and Technology Award of Hubei Province
2012 Outstanding Medicinal Award of Wuhan University
2013 Young talent of Medical Industry
2014 The Outstanding Young Scientist of Hubei Province
Publications
1. Yin Shen*, Melissa Ann F. Rampino, Reed C. Carroll, and Scott Nawy. G-protein-mediated inhibition of the Trp channel TRPM1 requires the Gβγ dimer. PNAS 2012 May 29;109(22):8752-7.
2. Shen Y*, J. Alexander Heimel , Maarten Kamermans , Neal S. Peachey , Ronald G. Gregg, Scott Nawy. A transient receptorpotential-like channel mediates synaptic transmission in rod bipolar cells. J Neurosci. 2009 May 13;29(19):6088-93.
3. Zhi Li, Tao He, Ke Du, Yi-Qiao Xing*, Yuan-Min Run , Yin Shen*. Inhibition of Oxygen-Induced Ischemic Retinal Neovascularization with Adenoviral 15-Lipoxygenase-1 Gene Transfer via Up-Regulation of PPAR-γ and Down-Regulation of VEGFR-2 Expression. PLOS One, 9(1):e85824,2014.
4. Yuan-yuan Chen, Shi-liang Liu, Dan-ping Hu, Yi-qiao Xing*, Yin Shen*. N-Nitroso-N-methylurea Induced Retinal Degeneration in Mouse. Experimental Eye Research, Pages 102–113, 2014.
5. Wen Fan, Yiqiao Xing, Yongmei Zhong, Changzheng Chen, Yin Shen*. Expression of NMDA receptor subunit 1 in the rat retina. Acta Histochem. 2013 Jan;115(1):42-7.
6. Zhi Li,Tao He, Ke Du,Yi-Qiao Xing,Yuan-Min Run,Ying Yan, Yin Shen*. Overexpression of 15-lipoxygenase-1 in oxygen-induced ischemic retinopathy inhibits retinal neovascularization via downregulation of vascular endothelial growth factor-A expression. Mol Vis. 2012;18:2847-59.
7. Li Na Wu, Tao He, Yi Qiao Xing, and Yin Shen. Incidence of Terson’s Syndrome in Patients With SAH in a Chinese Hospital. Curr Eye Res. 2013 Jan;38(1):97-101.
8. Ying Yan, Tao He, Yin Shen, Xiao Chen, Bo Diao, Zhi Li, Qing Liu, Yi-Qiao Xing. Adenoviral 15-Lipoxygenase-1 Gene Transfer Prevent Hypoxia-induced Proliferation of Retinal Microv ascular Endothelial Cells. Int J Ophthalmol. 2012; 5(5): 562–569.
9. Peachey NS, Pearring JN, Bojang P Jr, Hirschtritt ME, Sturgill-Short G, Ray TA, Furukawa T, Koike C, Goldberg AF, Shen Y, McCall MA, Nawy S, Nishina PM, Gregg RG. Depolarizing bipolar cell dysfunction due to a Trpm1 point mutation.J Neurophysiol. 2012 Nov;108(9):2442-51
10. Jillian Pearring, Pasano Bojang Jr, Yin Shen, Chieko Koike, Takahisa Furukawa, Scott Nawy, and Ronald Gregg. A role for nyctalopin, a small leucine rich repeat protein, in localizing the TRPM1 channel to retinal depolarizing bipolar cell dendrites. Journal of Neuroscience 2011 Jul 6;31(27):10060-6.
11. Snellman J, Kaur T, Shen Y, Nawy S. Regulation of ON bipolar cell activity. Progress of Retina Eye Research. 2008 Apr 6.
12. Shen Y, Liu XL, Yang XL. N-methyl-D-aspartate receptors in the retina. Molecular Neurobiology. 2006 Dec;34(3):163-79.
13. Shen Y, Zhang M, Yang XL. Functional NMDA receptors in carp outer retina. Neurosignals. 2006 Oct 17;15(437):174-179.
14. Shen Y, Chen L, Ping Y, Yang XL. Glycine modulates the center response of ON type rod-dominant bipolar cells in carp retina. Brain Reseach Bulletin. 2005 Nov 30;67(6):492-7.
15. Huang H, Luo DG, Shen Y, Zhang AJ, Yang R, Yang XL. AMPA receptor is involved in transmission of cone signal to ON bipolar cells in carp retina. Brain Research. 2004 Mar 26;1002(1-2):86-93.
Shen Y, Zhang AJ, Yang XL. Uncoupling of horizontal cells alters the receptive fields of retinal bipolar cells. Neuroreport. 2003 Dec 2;14(17):2159-62.