Personal Information
Name | YUAN, Zhanpeng | ![]() |
School or College | School of Public Health | |
Gender | Male | |
Position Title | Professor of Toxicology | |
Website | http://sph.whu.edu.cn/info/1105/2232.htm | |
zpyuan@whu.edu.cn | ||
Office Address | Rm. 419, Bldg. No.1, Medical Campus |
Research Interest
·Molecular toxicological mechanism of dioxins and heavy metals with respect of genes involved in tissue maintenance
·Biomarkers of environmental exposures of dioxins and heavy metals
·Bio-detection techniques of dioxins and heavy metals in foodstuff
·Toxicological techniques for drug research and development
Education
·Wuhan University School of Life Sciences, B.Sc. in Cell Biology, 1987
·New York University School of Medicine
Sackler Inst. of Basic Medical Sciences Graduate Program, M.Sc., 1997
Nelson Inst. of Environmental Health Sciences, Ph.D., 2003
Oversea Study and Visit
·See above
Honours and Awards
·Scholarship grant of Outstanding Doctoral Graduate Thesis Project from the Hudson River Foundation (USA), 1999-2001
·Graduate Travel Award of the Society of Toxicology (USA) for Annual Meeting, 2001
Publications
·Wang, H., Tang, L., Tang, Y.*, Z. Yuan*. 2014. SAR analyses and biological studies of synthesized podophyllum derivatives obtained by N linkage modification at C-4 position. Bioorganic & Medicinal Chemistry: DOI 10.1016/j.bmc.2014.08.025
·Zhao, W.1, Chen1, L., Li, H., Wang, D., Li, D., Chen, T., Yuan, Z.*, Y. Tang*. 2014. A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4′-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation. Bioorganic & Medicinal Chemistry 22 (11): 2998-3007.
·Yuan, Z., Courtenay, S., Chambers, R.C., Wirgin, I. 2006. Evidence of spatially extensive resistance to PCBs in an anadromous fish of the Hudson River. Environ Health Perspectives 144 (1): 77-84.
·Yuan, Z., Courtenay, S., and I. Wirgin. 2006. Comparison of hepatic and extra hepatic induction by graded doses of aryl hydrocarbon receptor agonists in Atlantic tomcod from two populations. Aquatic Toxicology 76(3):306-320.